LAY DESIGNERS CAN design TOO
C ontrast
R epition
A lignment
P roximity
For some reason I am not seeing this acronym the author speaks of? Well this is no C.R.A.P. little handbook. I found this to be a simple yet brilliant way of getting the most important design elements across. (are there really others?)I think Mr. Williams has concluded that a page or other design in order to be attractive and catchy must be unified through these 4 design elements, in order to maintain ease of readability and to get the point across. If all 4 elements are working together each one must cohere to the other.
However in my personal opinion if you have to sacrifice three in order to appear un-barbaric, I would start with alignment. I think this is the most important.
If these 4 are building blocks, I would say that alignment is the foundation. From there, if you were to somehow rearrange it, you must then use repetition, then proximity and the contrast to drive the point home. All working together to form something that is very deliberate and effective.